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Updated: Jul 1, 2025

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在老鼠肺部的新型DNA甲基化变化与慢性吸烟相关

Chinonye Doris Onuzulu1, Samantha Lee1, Sujata Basu2,3

  • 1Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada.

Epigenetics
|March 4, 2024
PubMed
概括

吸烟会改变肺部DNA甲基化模式,影响与COPD和癌症相关的基因. 这项研究强调了检查肺组织的重要性,以了解吸烟.

关键词:
慢性吸烟 长期吸烟通过DNA甲基化.整个表观基因组的整个表观基因组.肺功能 肺功能 肺功能

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Epigenetic Regulation01:37

Epigenetic Regulation

Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
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