母亲抑郁症状对后代执行功能的影响:系统性审查
Júlia de Souza Rodrigues1, María Pastor-Valero2, Lucas R Trambaiolli3
1Departamento de Medicina Preventiva, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil. Department of Public Health, History of Science and Gynecology, Faculty of Medicine, Miguel Hernández University, Campus de San Juan, Alicante, Spain.
母亲抑郁症会对儿童的执行功能产生负面影响. 这一系统性审查强调了有害影响,强调需要对症状严重程度和时间进行进一步研究.
科学领域:
- 发展心理学 发展心理学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 孕产妇抑郁症是一个重大的公共卫生问题.
- 执行功能 (EF) 是日常运作的关键认知过程.
- 了解母亲心理健康对儿童发育的代际影响至关重要.
研究的目的:
- 系统地审查现有的关于母性抑郁暴露对后代执行功能 (EFs) 影响的文献.
- 综合有关母亲抑郁症状与儿童认知发育之间的联系的证据.
主要方法:
- 按照PRISMA的指导方针,对主要数据库 (MEDLINE,ScienceDirect,LILACS,PsycINFO,SciELO) 进行了系统的文献搜索.
- 用NHLBI质量评估工具对33项队列研究 (38,981名参与者) 进行了质量评估.
- 使用推,评估,开发和评估 (GRADE) 框架等级来评估证据.
主要成果:
- 在33项包括的队列研究中,有24项表明,母亲抑郁症状对后代的EFs有不利影响.
- 在研究中观察到显著的异质性,排除了元分析.
- 潜在的调解机制包括胎儿编程,遗传因素和父母的做法.
结论:
- 在母亲的抑郁症状和后代的执行功能之间存在着一致的负面联系.
- 建议进行进一步的研究,以探索症状慢性,严重程度和敏感发育期对后代EFs的影响.
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