黑人美国人的歧视和心血管健康:探索炎症作为一种机制和感知控制作为一种保护因素
Carrington C Merritt1, Keely A Muscatell
1From the Department of Psychology and Neuroscience (Merritt, Muscatell), Lineberger Comprehensive Cancer Center (Muscatell), and Carolina Population Center (Muscatell), University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Psychosomatic medicine
|March 4, 2024
概括
歧视通过炎症增加了黑人美国人的心血管风险. 感知控制可以提供对这些影响的保护,建议潜在的干预目标.
科学领域:
- 社会流行病学 社会流行病学
- 心理神经免疫学 心理神经免疫学
- 健康差距 研究 研究 研究 研究
背景情况:
- 系统性炎症是将歧视与心血管疾病联系起来的潜在机制.
- 心理社会因素,如感知控制,可能会缓冲歧视对健康的不利影响.
- 心血管健康的种族健康差异是一个重大的公共卫生问题.
研究的目的:
- 调查系统性炎症是否调解了歧视和心血管健康之间的关系.
- 检查感知控制是否缓解了歧视,炎症和心血管健康之间的关联.
- 探索黑人美国人歧视对心血管疾病的潜在保护因素.
主要方法:
- 美国中年期的347名非西班牙裔/拉丁裔黑人成年人的横截面研究.
- 通过自我报告评估感知控制和日常歧视.
- 使用C反应蛋白 (CRP),互白素-6 (IL-6),纤维素原和瘤缩因子α测量炎症;根据心脏病,高血压和/或中风的发病率评估心血管健康.
主要成果:
- 反应性C蛋白 (CRP) 和纤维素原水平调解了歧视和心血管疾病之间的关联.
- 感知控制显著缓解了歧视和CRP水平之间的关系.
- 在将歧视与心血管疾病联系起来时,炎症的调解作用主要表现在受感控制较低的个体中.
结论:
- 炎症作为一种经验机制,将歧视经历与黑人美国人的心血管疾病联系起来.
- 感知控制显示出潜在的保护作用,减轻歧视对心血管健康的负面影响.
- 关于控制的信念是旨在减少黑人美国人的歧视相关心血管风险的干预措施的有希望的目标.
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