,NLRC3TNFα+ Th17

Lingyan Ren1,2, Guangjun Liu3, Yun Bai3

  • 1Department of Orthopedics, Guizhou Provincial People's Hospital, Guiyang, Guizhou Province, 550003, China.

Journal of molecular medicine (Berlin, Germany)
|March 4, 2024
PubMed
概括

含有3 (NLRC3) 的NOD类受体家族CARD域通过抑制T助手17 (Th17) 细胞反应来防止骨损失. 缺乏NLRC3会通过促进Th17细胞的积累和骨质细胞形成来加剧骨质疏松症.

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