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外核酶III驱动的DNAzyme步行器:微RNA诊断的电化学策略

Dengke Li1, Qiuyan Huang2, Kun Wang3

  • 1Department of Rehabilitation Medicine, the Affiliated Huaian No.1 People's Hospital of Nanjing Medical University, Huaian, 223300, China. lidengke3278@163.com.

Mikrochimica acta
|March 4, 2024
PubMed
概括

一个新的DNAzyme步行者系统使敏感的microRNA检测能够用于早期疾病诊断. 这种基于外核酶III的方法简化了护理点的测试,并允许同时检测多个microRNA.

关键词:
级联放大器的级联放大器一个DNA步行者.DNAzyme; 修改后的黄金电极异核酶III可以产生异核酶.方形波电压测量 方形波电压测量

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DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...