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Updated: Jul 1, 2025

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SOX9通过在神经纤维瘤中抑制PCOLCE来促进原VI分泌

Xuan Yao1,2, Bo Wang1,2, Yuanping Su1,2

  • 1Department of Neurosurgery and Laboratory of Neurosurgery, Lanzhou University Second Hospital, Lanzhou, 730030, Gansu, China.

Molecular neurobiology
|March 4, 2024
PubMed
概括

神经纤维素瘤类型1 (NF1) 涉及NF1基因突变和神经纤维瘤瘤. 这项研究揭示了SRY-box转录因子9 (SOX9) 通过通过procollagen C-endopeptidase增强剂 (PCOLCE) 激活增加原VI来促进瘤生长.

关键词:
原蛋白分泌的时间纤维细胞细胞.神经纤维瘤是一种神经纤维这就是PCOLCE,PCOLCE.这就是SOX9的SOX9.

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