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Updated: Jun 24, 2026

Long-term Silencing of Intersectin-1s in Mouse Lungs by Repeated Delivery of a Specific siRNA via Cationic Liposomes. Evaluation of Knockdown Effects by Electron Microscopy
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阴性胆固醇依赖的LNP输送到肺干细胞,肝脏和心脏

Afsane Radmand1,2, Hyejin Kim3, Jared Beyersdorf3

  • 1Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology, Atlanta, GA 30332.

Proceedings of the National Academy of Sciences of the United States of America
|March 4, 2024
PubMed
概括

将带电元件添加到脂质纳米粒子 (LNP) 中,会影响它们传递mRNA的位置. 阴阳性胆固醇和阴阳性辅助脂质显示出不同的输送模式,为目标输送提供了新的策略.

关键词:
在LNP中使用LNP.条码编码 条码编码它们是mRNARNA.纳米颗粒是一种纳米粒子.这就是scRNA-seqq.

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