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Updated: Jul 1, 2025

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克西兰酶A双基因突变对基质特异性和结构动态的影响

Meagan E MacDonald1, Nicholas G M Wells2, Bakar A Hassan3

  • 1Department of Chemistry, Wesleyan University, Middletown, CT 06459, United States; Department of Molecular Biology and Biochemistry, Wesleyan University, Middletown, CT 06459, United States.

Journal of structural biology
|March 4, 2024
PubMed
概括

在活性部位附近的酶灵活性会影响活性. 克西兰酶A (XylA) 的双重突变改变了基质特异性,有利于更开放的指形状,影响了酶功能.

关键词:
化学自由能量模拟的炼化学模拟.化学转移扰动 化学转移扰动中间交易所线路扩展具体性 具体性 具体性克西兰酶A是一种

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