高收入国家的辅助生殖技术的经济评估:系统审查
Emily Olive1, Claudia Bull2, Adrienne Gordon1
1Discipline of Obstetrics, Gynaecology and Neonatology, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia.
Human reproduction (Oxford, England)
|March 4, 2024
概括
大多数辅助生殖技术 (ART) 干预措施,如对阳积体 (PGT-A) 的植入前遗传检测和对不明原因不育的ICSI,都不具有成本效益. 需要进一步的研究,以确定不孕症治疗的成本节约策略.
科学领域:
- 生殖医学 生殖医学
- 卫生经济学 卫生经济学
- 不孕症治疗 不孕症治疗
背景情况:
- 辅助生殖技术 (ART) 干预措施在全球范围内越来越多地使用.
- 对ART干预措施的经济评估对于知情决策至关重要.
- 之前的研究已经强调了需要对各种ART程序的成本效益评估.
研究的目的:
- 系统地审查和确定在高收入国家哪些辅助生殖技术 (ART) 干预措施具有成本效益.
- 评估不同ART干预措施的经济证据,以指导未来的投资.
主要方法:
- 对2011年1月以来发表的研究进行了七个数据库的系统审查.
- 包括的研究检查了治疗不孕症的ART干预措施,其中包括经济评估组成部分.
- 两个独立审查员评估了资格,成本效益和报告质量.
主要成果:
- 该审查包括来自11个高收入国家的40项研究,其中大多数专注于成本效益分析.
- 发现PGT-A和ICSI等高成本干预措施对于无法解释的不孕不育不太可能具有成本效益,因为效率的提高很小.
- 使用生物类似药或HMG的一些卵巢刺激策略更便宜,但影响了临床有效性.
结论:
- 许多广泛使用的ART干预措施,包括针对特定疾病的PGT-A和ICSI,没有证明成本效益.
- 需要研究成本降低策略,以改善获得ART的机会.
- 这一审查可以帮助资助者优化投资,以获得不孕症治疗中更好的结果.
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