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Updated: Jul 1, 2025

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内皮细胞通过构建基底膜,作为肌纤维细胞的支架,来调节膜形态发生

Haruko Watanabe-Takano1, Katsuhiro Kato2, Eri Oguri-Nakamura3

  • 1Department of Molecular Pathophysiology, Institute of Advanced Medical Sciences, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8602, Japan. t-haruko@nms.ac.jp.

Nature communications
|March 4, 2024
PubMed
概括

内皮细胞 (ECs) 通过构建引导肌纤维细胞的底层膜来编排肺气膜生成. 这一对于肺部发育至关重要的过程涉及Rap1和整蛋白信号,揭示了器官形态发生的新型EC驱动机制.

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