相关实验视频

Updated: Jul 1, 2025

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

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在头癌中出现反复的UBE3C-LRP5转位,具有治疗意义

Bhasker Dharavath1,2, Ashwin Butle1,3, Akshita Chaudhary1

  • 1Integrated Cancer Genomics Laboratory, Advanced Centre for Treatment, Research, and Education in Cancer, Kharghar, Navi Mumbai, Maharashtra, 410210, India.

NPJ precision oncology
|March 4, 2024
PubMed
概括

在头癌中,一种新的UBE3C-LRP5基因融合通过激活Wnt/β-catenin信号来驱动瘤生长. 这种融合呈现出一种潜在的治疗标,在临床前模型中,pyrvinium pamoate显示出有希望的结果.

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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing09:49

Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing

Published on: July 5, 2019

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Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

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