在老年人中,氧化平衡得分和肉症之间的关联
Marzieh Mahmoodi1,2, Zainab Shateri3, Seyed Alireza Nazari4
1Department of Clinical Nutrition, School of Nutrition and Food Sciences, Shiraz University of Medical Sciences, Shiraz, Iran.
Scientific reports
|March 4, 2024
概括
较高的氧化平衡评分 (OBS),表明饮食中的抗氧化剂比亲氧化剂更多,与老年人患症的几率较低无关. 这项研究调查了伊朗老年人饮食氧化平衡与与年龄相关的肌肉损失之间的联系.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 肌肉生理学 肌肉生理学
背景情况:
- 萨尔科佩尼亚是一种渐进的骨肌肉疾病,与氧化压力有关.
- 氧化平衡评分 (OBS) 量化了饮食中的抗氧化剂和亲氧化剂摄入量.
- 了解影响肉症的饮食因素对于老龄化人口至关重要.
研究的目的:
- 评估伊朗老年人中氧化平衡评分 (OBS) 和肉眼之间的关联.
- 为了调查一种偏爱抗氧化剂而非亲氧化剂的饮食是否会影响肉症的风险.
- 探索饮食氧化平衡在与年龄相关的肌肉衰退中的作用.
主要方法:
- 病例对照研究涉及80名患有肉症的个人和80名对照人群,按性别匹配.
- 萨尔科佩尼亚评估包括骨肌肉质量指数 (SMI),手握强度 (HGS) 和步行速度.
- 抗氧化剂和亲氧化剂的饮食摄入量使用食物频率问卷 (FFQ) 进行了评估.
- 条件后勤回归分析被用来确定OBS和肉症之间的关联.
主要成果:
- 在双变体分析中,较高的OBS三位体 (第二和第三) 与第一三位体相比, Sarcopenia的几率较低.
- 然而,经过对潜在混因素进行调整后,这种关联变得无意义.
- 这项研究发现,较高的OBS与老年人肉症的几率降低之间没有显著的关系.
结论:
- 在伊朗的老年人中,较高的氧化平衡得分 (OBS) 与较低的麻症几率没有显著的关联.
- 与亲氧化剂相比,富含抗氧化剂的饮食模式似乎不能在这个人群中保护人免受.
- 需要进一步的研究来阐明饮食,氧化应激和萨科佩尼亚之间的复杂关系.
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