恶性瘤通过肺叶的分布和特征
Yngvar Nilssen1, Odd Terje Brustugun2,3, Lars Fjellbirkeland3,4
1Department of Registration, Cancer Registry of Norway, Box 5313 Majorstuen, Oslo, 0304, Norway.
BMC pulmonary medicine
|March 4, 2024
概括
肺癌倾向于右上叶,类似于其他吸入性疾病. 瘤的位置会影响治疗选择,如切除,但不会影响生存结果.
科学领域:
- 肺部医学 肺部医学
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
背景情况:
- 传统的肺瘤分析侧重于大小,位置和透.
- 肺瘤在不同叶区的分布和特征需要进一步研究.
- 了解叶片变异可能会影响诊断,治疗和患者的结果.
研究的目的:
- 研究恶性肺瘤在不同肺叶的分布和特征.
- 为了确定肺癌的诊断,治疗和结果是否因瘤的位置而有所不同.
- 根据叶片分布,识别肺癌的潜在倾向部位.
主要方法:
- 分析了2018年至2022年期间诊断的10849名肺癌患者.
- 评估每个肺叶内的瘤位置和特征.
- 根据叶片体积计算每个叶片的相对瘤比例.
主要成果:
- 与其他叶片相比,右上叶的相对瘤比例 (1.77) 显著更高.
- 右中叶的神经内分泌瘤比例最高 (26.1%).
- 在调整了关键患者因素后,瘤位置独立预测了手术切除,但不能预测存活.
结论:
- 右上叶是肺癌倾向的部位,反映了结核病和肺病中看到的模式.
- 这种偏好可能与将吸入的物质引导到上和右肺的空气流模式有关.
- 腰部瘤的位置会影响治疗策略,特别是手术干预.
相关概念视频
Gross Anatomy of the Lungs
1.8K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
1.8K
Cancer
48.5K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
48.5K
Other Pulmonary Disorders
838
Respiratory disorders encompass a range of conditions with varying levels of severity. Asthma, marked by chronic airway inflammation and hypersensitivity, is one such condition. It can lead to airway obstruction due to factors like bronchial spasms, mucosal edema, increased mucus secretion, or epithelial damage. Asthma triggers are diverse, ranging from allergens to emotional upset, and treatment focuses on both immediate relief through bronchodilators and long-term inflammation suppression.
838
Tumor Progression
6.3K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.3K
lncRNA - Long Non-coding RNAs
8.6K
In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
8.6K


