评估Truenat在肺外结核诊断中的有用性 - 一个NRL的经验
Priya Rajendran1, Lavanya Jayabal2, Mythili Venkatesan1
1ICMR -National Institute for Research in Tuberculosis, Chennai, India.
概括
特鲁纳特MTB测试显示出对诊断肺外结核 (EPTB) 的前景. 虽然不适合随访,但它为初始EPTB诊断提供了快速,经济高效的选择.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 分子诊断学 分子诊断学
背景情况:
- 诊断肺外结核 (EPTB) 存在重大挑战.
- 关于Truenat MTB测试对EPTB的有用性存在有限的数据,与Xpert测试的广泛研究不同.
研究的目的:
- 评估Truenat MTB测试对EPTB的诊断有用性.
主要方法:
- 这项研究涉及在奈 (2021-2022) 怀疑或接受EPTB治疗的患者.
- EPTB样品经过涂抹显微镜,培养和Truenat MTB测试.
主要成果:
- 在195个样本中,38个 (19.4%) 对EPTB呈阳性.
- 与复合参考标准相比,Truenat的MTB测试显示了60%的灵敏度和100%的特异性.
结论:
- 特鲁纳特MTB是一种快速,具有成本效益的分子测试,适用于诊断假定的EPTB.
- 该测试不建议用于监测患者或随访样本.
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