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淋巴结生物模拟支架增强了针对固体瘤的CAR-T疗法

Ziyan Liao1,2,3, Jie Jiang4, Wei Wu5

  • 1National Key Laboratory of Advanced Drug Delivery and Release Systems, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.

National science review
|March 5, 2024
PubMed
概括

一种新的生物仿真支架通过改善细胞扩张和持久性,增强了固体瘤的仿真抗原受体 (CAR) -T细胞疗法. 这种方法提高了CAR-T细胞的有效性,为癌症治疗提供了新的希望.

关键词:
生物启发的生物材料癌症免疫疗法免疫疗法细胞治疗疗法细胞治疗疗法药物输送是药物输送的过程.

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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