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在社区药房进行病毒性肝炎检测和治疗:系统性审查和元分析
Mark J Hayes1, Emma Beavon1, Michael W Traeger1,2
1Burnet Institute, Melbourne, Australia.
EClinicalMedicine
|March 5, 2024
概括
社区药房有效地提高了型肝炎的检测和治疗率,特别是在针对风险人群时. 这支持世界卫生组织的目标,即到2030年消除病毒性肝炎.
科学领域:
- 公共卫生 公共卫生
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 世界卫生组织的目标是到2030年消除病毒性肝炎作为公共卫生威胁.
- 社区药房越来越多地因其在公共卫生干预中的作用而得到认可.
- 本综述评估了基于药房的B型和C型肝炎检测和治疗计划的有效性.
研究的目的:
- 评估社区药房计划对乙型肝炎和型肝炎的检测和治疗的有效性.
- 评估检测阳性并通过药房设置的护理级联进展的个人的比例.
- 为了比较基于药房的干预措施与传统的医疗保健环境.
主要方法:
- 对比性和单臂干预研究的系统审查和元分析.
- 在Medline,Embase,Cochrane CENTRAL和全球健康数据库中进行的搜索,截至2023年11月.
- 纳入标准涵盖了测试前的风险评估,测试,治疗前的评估,以及在药房中为乙型肝炎或C型肝炎提供治疗.
主要成果:
- 包括27项研究 (26项针对C型肝炎,4项针对B型肝炎).
- 型肝炎抗体阳性的综合比例为16.6%,在目标高风险群体中显著高 (32.5%).
- 基于药房的治疗前评估出席率 (92.7%) 和治疗启动率 (85.6%) 很高,与非药房设置相比.
结论:
- 社区药房在扩大型肝炎检测和治疗机会方面是有效的.
- 药店的有针对性的测试显著增加了阳性检测率.
- 需要进一步的研究,以优化社区药房的乙型肝炎护理.
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