在更年期妇女中听力损失的观察性研究
R B Namasivaya Navin1, S Prabakaran1, D Balaji1
1Department of Otorhinolaryngology (ENT), Chettinad Hospital and Research Institue, Chettinad Academy of Research and Education, Kelambakkam, Tamilnadu 603103 India.
概括
与年龄相关的听力损失是一个越来越令人担忧的问题. 这项研究发现,低血糖控制和更年期与50岁以上女性的感觉神经听力损失有显著的关联.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 内分泌学 在内分泌学.
- 老年学是指老年学的学科.
背景情况:
- 与年龄相关的听力损失 (听力障碍) 和50岁以上成年人听力损失是重要的公共卫生问题.
- 虽然已知更年期妇女会出现听力损失,但尚未确定明确的因果关系.
- 糖尿病是一种普遍的疾病,可能会影响各种身体系统,包括听觉功能.
研究的目的:
- 研究更年期,糖尿病和成人女性听力损失之间的关系.
- 为了确定血糖控制是否与听力损失的患病率和严重程度有关.
- 探索更年期和糖尿病对听力健康的综合影响.
主要方法:
- 评估了158名更年期妇女的队列.
- 纯音调听力测试用于评估听力功能.
- 测量了糖化血红蛋白 (HbA1c) 水平,以评估血糖控制,以及临床病史和检查.
- 使用奇平方测试来分析变量之间的关联.
主要成果:
- 听力损失与年龄的增加 (chi-square=9.629,P=0.002) 和血糖管理不良 (chi-square=4.304,P=0.038) 在统计学上是相关的.
- 在158名参与者中,21.5% (N=34) 呈现双侧神经感官听力损失.
- 低血糖控制和更年期与神经感官听力损失有很强的关联.
结论:
- 衰老和低于最佳的血糖控制是绝经妇女听力损失的重要危险因素.
- 糖尿病,特别是血糖管理不良的糖尿病,在这个人口群体中加剧了听力损失.
- 建议对更大种群进行进一步的研究和激素评估,以阐明这些关联.
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