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对自身免疫内耳疾病患者临床概况的回顾性研究

Sreenivas V¹, Rosemary Sen¹, Pratibha C B¹

¹Department of Otorhinolaryngology, Head and Neck Surgery, St John's Medical College Hospital, Bangalore, India.

Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India

|March 5, 2024

概括

自免疫内耳疾病 (AIED) 导致双边神经神经感官听力损失. 早期诊断和使用类固醇治疗为听力改善提供了谨慎的预后,重点是康复.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
免疫学免疫学免疫学
听力学听力学是指听力学.

背景情况:

双边感应神经听力损失显著影响生活质量.
自身免疫病因是双边听力损失的一个罕见但重要的原因.
自免疫内耳疾病 (AIED) 呈现出对类固醇反应的波动性听觉静脉症状.

研究的目的:

评估符合AIED标准的患者.
了解AIED的临床特征.
评估AIED患者对医疗治疗的反应.

主要方法:

快速渐进的双边听力损失患者的回顾性图表审查.
包括详细的临床病史,检查结果,血液检查和听力图.
对全身类固醇和内类固醇治疗反应的分析.

主要成果:

研究包括6名患者 (3名男性,3名女性),年龄在24-35岁之间.
3名患者患有初级AIED,3名患者患有系统性自身免疫性疾病的次要听力损失.
对全身类固醇的反应有所不同;初级AIED患者也接受了肠内类固醇.

结论:

AIED是一种排除的诊断,需要高度的临床怀疑.
对自身免疫病因的评估对于双边渐进性神经感官听力损失至关重要.
目前AIED治疗的主要支柱包括口服和内耳内类固醇,预后谨慎,重点是早期康复.

关键词:

自免疫性内耳疾病是什么?双边渐进的感觉神经神经听力损失.

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