侵入性鼻炎在COVID患者中呈现与轨道并发症:粘液是唯一的原因吗?
Kouser Mohammadi1, S M Azeem Mohiyuddin1, K C Prasad1
1Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar, India.
概括
在COVID-19大流行期间,细菌性鼻炎经常被误诊为真菌性鼻炎. 早期发现细菌感染对于适当的治疗和改善患者的治疗结果至关重要.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 传染性疾病 传染性疾病
- 眼科医生 眼科 眼科
背景情况:
- 在COVID-19大流行的第二波疫情中,真菌感染的高死亡率Mucormycosis增加了.
- 细菌性侵袭性鼻炎可以模仿真菌性鼻炎,使诊断和治疗复杂化.
- 氨基氨酸B是菌菌病的主要治疗方法,是有毒的,昂贵的,并且对细菌感染无效.
研究的目的:
- 在COVID-19大流行期间识别具有轨道并发症的侵入性鼻炎的病因病因.
- 确定这些患者的诱导因素和治疗结果.
- 区分细菌性鼻炎和真菌性鼻炎,以进行适当的治疗降级.
主要方法:
- 对33名患有COVID相关的侵入性鼻炎和轨道并发症的患者进行了回顾性观察性研究.
- 临床评估,鼻科检查,用于显微镜和培养的鼻子拭子,以及放射性成像 (CECT/MRI).
- 治疗包括Liposomal Amphotericin B和手术脱bridement,根据微生物学发现进行调整.
主要成果:
- 在48.5%的患者中发现了细菌感染,在27.3%的患者中发现了真菌感染,在24.2%的患者中发现了混合感染.
- 在细菌和真菌感染中观察到状形成和组织亡等临床表现.
- 轨道并发症,包括持续性眼和视力恶化,更多与真菌和混合感染有关,而细菌性鼻炎则显示适当的抗生素有所改善.
结论:
- 在COVID-19大流行期间,侵袭性细菌性鼻炎的诊断不足.
- 区分细菌和真菌鼻炎对于有效治疗和防止不必要的抗真菌使用至关重要.
- 准确的诊断允许针对性的抗生素治疗,导致COVID相关的侵入性鼻炎与轨道并发症的更好的结果.
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