与治疗相关的神经内分泌前列腺癌与BRCA2生殖系突变治疗olaparib
Riko Ikeda1, Yoh Matsuoka1, Masaharu Inoue1
1Department of Urology Saitama Cancer Center Saitama Japan.
IJU case reports
|March 5, 2024
概括
奥拉巴里布在患有与治疗相关的神经内分泌前列腺癌和BRCA2突变的患者中显示出1年的疗效. 这种PARP抑制剂为这种罕见的癌症亚型提供了潜在的治疗选择.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 前列腺癌研究 研究前列腺癌研究
背景情况:
- 神经内分泌前列腺癌 (NEPC) 是一种罕见且具有攻击性的亚型.
- 与治疗相关的NEPC可以在前列腺腺癌的雄激素剥夺治疗后出现.
- 针对性疗法在与治疗相关的NEPC中的疗效在很大程度上仍然未被描述.
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