更年期妇女的睡眠时间和抑郁症之间的关联:一个基于人口的研究
1Department of Medicine, Shandong Liming Science and Technology Vocational College, Jinan, China.
Frontiers in endocrinology
|March 5, 2024
概括
睡眠时间影响更年期妇女50岁以上的抑郁风险. 短时间睡眠和长时间睡眠都与抑郁症患病率的增加有关,这凸显了平衡睡眠模式对心理健康的重要性.
科学领域:
- 生殖医学 生殖医学
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 更年期与各种健康变化有关,包括对心理健康的潜在影响.
- 睡眠障碍在更年期妇女中很常见,可能会影响情绪障碍.
研究的目的:
- 调查50岁及以上的绝经妇女睡眠时间和抑郁症患病率之间的独立关系.
- 探索非线性关联,并确定与抑郁风险相关的睡眠时间的潜在值.
主要方法:
- 利用2011-2020年国家健康和营养检查调查 (NHANES) 数据进行横截面分析.
- 采用多变量线性回归,平滑曲线和值效应评估来分析睡眠时间和抑郁症得分.
- 根据生活方式因素和并发症进行了子组分析.
主要成果:
- 与正常睡眠时间相比,短睡眠时间增加了17% (OR=1.17) 的抑郁症患病率,长睡眠时间增加了86% (OR=1.86).
- 在睡眠时间和抑郁症得分之间观察到U形关系,转折点在7.5小时.
- 睡眠时间不到7.5小时 (β=-0.81) 和超过7.5小时 (β=0.80) 都与抑郁症风险的增加显著相关.
结论:
- 睡眠时间与绝经妇女的抑郁症有显著的关联.
- 睡眠时间不够和过长都与这一群体患抑郁症的风险更高有关.
- 保持平衡的睡眠时间对于在绝经期间管理抑郁风险至关重要.
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