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Updated: Jul 1, 2025

Multiplexed Immunofluorescence Analysis and Quantification of Intratumoral PD-1+ Tim-3+ CD8+ T Cells
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我们还可以使用三级淋巴体结构作为黑色素瘤免疫治疗反应的预测生物标志物吗?

Francine Padonou1, Thila Vanhulst, Mireille D Langouo-Fontsa

  • 1Molecular Immunology Laboratory, Institut Jules Bordet, Université Libre de Bruxelles, Brussels (Anderlecht), Belgium.

Current opinion in oncology
|March 5, 2024
PubMed
概括

三级淋巴体结构 (TLS) 是有前途的生物标志物,可预测黑色素瘤患者的免疫治疗反应. 它们的存在与改善的生存率相关,这表明它们在个性化癌症治疗中发挥了作用.

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相关概念视频

Tumor Immunotherapy01:27

Tumor Immunotherapy

Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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