在1476名患者的前列腺动脉栓塞的辐射暴露和相关风险的多中心量化
Raj Ayyagari1, Saumik Z Rahman1, Kevin Grizzard1
1From the Boston Medical Center, 75 Albany Street, Boston, MA 02118 (R.A.); Yale University School of Medicine, New Haven, Conn (S.Z.R., K.G., A.M., L.H.S., R.S.M.); University of Miami Miller School of Medicine, Miami, Fla (S.B., A.R.); Centro Hospitalar Universitário de Lisboa Central, Lisbon, Portugal (T.B.); Universidade de São Paulo Faculdade de Medicina, São Paulo, Brazil (F.C.C.); University of South Florida Morsani College of Medicine, Tampa, Fla (C.D.); Icahn School of Medicine at Mount Sinai, New York, NY (A.F.); Prostate Centers Raleigh, Raleigh, NC (A.I.); Weill Cornell Medical College, New York, NY (T.M.); University of California Los Angeles David Geffen School of Medicine, Los Angeles, Calif (J.M.); Endovascular Consultants of Colorado, Lone Tree, Colo (C.N.); Northwestern University Feinberg School of Medicine, Evanston, Ill (R.S.); Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges-Pompidou, Paris, France (M.S.); and The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC (H.Y.).
前列腺动脉栓塞 (PAE) 对于良性前列腺增生是有效的,但辐射暴露是一个问题. 这项研究没有发现与辐射相关的90天不良事件,有效剂量的中位数为17.8mSv (固定单位) 和12.3mSv (移动单位).
科学领域:
- 干预性放射学 干预性放射学
- 医疗成像医学成像
- 辐射瘤学 辐射瘤学
背景情况:
- 前列腺动脉栓塞 (PAE) 是一种对良性前列腺激增的微创治疗方法.
- 了解PAE患者的辐射暴露和风险至关重要.
研究的目的:
- 在接受PAE的患者中量化辐射剂量.
- 在PAE之后评估与辐射相关的不良事件.
主要方法:
- 对10个国际中心的1476名患者 (2014-2021) 的回顾性研究.
- 使用克尔马面积和转换因子计算有效辐射剂量.
- 使用回归分析评估剂量与患者/程序因素之间的相关性.
主要成果:
- 固定式光镜装置的有效剂量中位数为17.8mSv,移动式光镜装置的有效剂量为12.3mSv.
- 辐射剂量与体重指数和光镜时间正相关.
- 没有报告与辐射相关的90天不良事件.
结论:
- 根据光镜装置的类型,PAE辐射剂量有所不同.
- 没有观察到与辐射暴露相关的短期不良事件.
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