全血复苏有什么新鲜事? 在创伤室和更远的地方
Stacy L Coulthard1,2, Lewis J Kaplan1,3, Jeremy W Cannon1,2
1Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
Current opinion in critical care
|March 5, 2024
概括
全血 (WB) 复苏,包括温暖的新鲜全血 (FWB) 和低标位的冷储全血 (LTOWB),越来越多地用于出血性休克. 这种方法改善了早期的存活率,并减少了创伤患者的血液制品使用.
科学领域:
- 紧急医疗 紧急医疗
- 关键的护理关键的护理
- 血液学 血液学 血液学
背景情况:
- 输血治疗对于严重疾病和创伤至关重要.
- 全血 (WB) 复苏正在经历严重出血的复苏.
- 出血性休克管理是一个关键的重点.
研究的目的:
- 为了检查最近全血 (WB) 复苏在出血休克患者的复苏.
- 审查WB在创伤和其他严重出血条件中的使用.
主要方法:
- 审查关于WB复苏的当前文献.
- 分析不同类型的WB:温暖的新鲜全血 (FWB) 和低标位的冷储全血 (LTOWB).
- 评估WB在军事和民用创伤和非创伤性出血性休克中的使用.
主要成果:
- 越来越多的证据支持WB在创伤中进行静血复苏.
- 使用WB可以减少血液产品的整体利用率,并改善早期死亡率.
- 没有观察到对ICU停留时间或感染率的不良影响.
- 应用范围扩展到医院前和非创伤性休克.
结论:
- 全血 (WB),作为FWB或LTOWB,支持在出血性休克时的静脉复苏.
- 对创伤的关注正在扩大到严重出血的其他原因.
- 需要进一步研究成本,疗效和患者的结果,以获得更广泛的WB应用.
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