在扩散的大B细胞淋巴瘤中,轨道的样反应
Frank Mei1, Snehaa Maripudi1, Robert N Hogan1
1Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Orbit (Amsterdam, Netherlands)
|March 5, 2024
概括
类反应 (SLR) 可以在各种器官中表现出来. 这项研究报告了第一例患有淋巴瘤和鼻逆转乳头瘤的患者的轨道SLR病例,强调恶性瘤是关键的差异诊断.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 眼科医生 眼科 眼科
背景情况:
- Sarcoid-like反应 (SLR) 呈现为非化颗粒瘤,通常通过成像检测.
- SLR与固体瘤,淋巴瘤和免疫疗法有关,通常会影响淋巴结,肺,,骨髓和皮肤.
- 区分SLR和肉类突发症依赖于缺乏系统性标准.
研究的目的:
- 报告第一个有记录的轨道单反相机的案例.
- 调查轨道SLR与并发性恶性瘤和其他疾病的关联.
- 为了强调考虑轨道非致病性颗粒瘤的恶性瘤的重要性.
主要方法:
- 一名患有扩散性大B细胞淋巴瘤和大 sinus逆转乳头瘤的患者的病例报告.
- 对轨道病变的组织病理学检查显示出非化性颗粒瘤.
- 对SLR和轨道颗粒状疾病现有文献的综述.
主要成果:
- 患者呈现了轨道SLR,这是一个罕见的表现.
- 发现了扩散型大B细胞淋巴瘤和逆向乳头瘤的存在.
- 轨道SLR在组织病理学上得到证实.
结论:
- 轨道SLR是一种非常罕见的发现.
- 恶性瘤,如淋巴瘤,应该是轨道非致病性颗粒瘤的差异诊断的主要考虑因素.
- 这一案例扩大了SLR的已知临床谱.
相关概念视频
Secondary Lymphoid Organs
1.5K
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
1.5K
B Cell Activation and Differentiation
1.7K
The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
1.7K
Accessory Structures of the Eye
1.5K
Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
1.5K


