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Updated: Jul 1, 2025

Techniques to Induce and Quantify Cellular Senescence
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PR55α控制的蛋白酸酶2A抑制p16的表达,并通过γ辐射阻断细胞衰老的诱导

Chitra Palanivel1, Lepakshe S V Madduri1, Ashley L Hein2

  • 1Department of Radiation Oncology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

Aging
|March 5, 2024
PubMed
概括

PR55α通过调节p16/RB通路独立于p53状态来抑制p16表达并阻止电离辐射诱导的细胞衰老. 这一发现揭示了PR55α在控制细胞循环停止中的新作用.

关键词:
在CDKN2A的位置.在PP2A中,PP2A是PP2A.在PR55α中使用.在 RB RB RB 的位置上.p1414 在这个问题上.p16 p16 在这个问题上.在 p53 里,p53 是一个 p53 的类型.γ-辐射的辐射

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