主要非反流性大尿道:自然史,随访和治疗
Giulio Rivetti1, Pierluigi Marzuillo2, Stefano Guarino1
1Department of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania "Luigi Vanvitelli", Via Luigi De Crecchio 2, 80138, Naples, Italy.
European journal of pediatrics
|March 5, 2024
概括
主要非反流性大尿道 (PMU) 是一种先天性尿道扩张,通常在产前诊断. 虽然许多病例自发地消失,但长期随访至关重要,尿管移植是手术干预的黄金标准.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 遗传异常 是一种先天性异常.
- 产前诊断 在产前诊断
背景情况:
- 主要非反流性大尿道 (PMU) 是一种与其他尿路异常无关的先天性尿道扩张.
- 它是由远端尿管功能障碍或狭窄引起的,并且是在产前水缩中常见的发现.
- PMU经常通过例行产前超声波来诊断.
研究的目的:
- 审查自然史,诊断方法和初级非反流性大尿路的管理策略.
- 强调长期随访和PMU当前治疗选择的重要性.
主要方法:
- 关于初级非反流性大尿道的现有文献的综述.
- 讨论诊断标准,包括产前超声波发现.
- 分析自然史,自发解决率和干预的指示.
主要成果:
- 大多数PMU病例无症状,自发消失,有利于非手术治疗.
- 外科干预仅适用于发烧性尿路感染,扩张恶化或功能下降的病例.
- 建议进行长期超声监测,因为可能出现晚发症状.
结论:
- 尿道移植与切除功能障碍部分是PMU的黄金标准手术治疗.
- 在某些特定情况下,内镜手术的成功率相当高.
- 对于患有持续性水尿氨缩症的患者,进行仔细的长期监测是必不可少的.
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