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Updated: Jul 1, 2025

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
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Gln-carba-ADPr-peptide的合成和宏域结合

Sander B Engelsma1, Aurelio Pio Nardozza2, Pieter de Saint Aulaire1

  • 1Gorlaeus Laboratories, Leiden Institute of Chemistry, Faculty of Science, Einsteinweg 55, 2333 CC, Leiden, the Netherlands.

Chembiochem : a European journal of chemical biology
|March 5, 2024
PubMed
概括

研究人员在谷氨酸上开发了一种稳定的模仿单-ADP-ribosylation,这是一个关键的翻译后修改,涉及到细胞信号传递. 这种carba-ADP-ribosylated可以对这种动态修饰进行关键的结构和生化研究.

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