相关实验视频

Updated: Jul 1, 2025

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins
16:10

A TIRF Microscopy Technique for Real-time, Simultaneous Imaging of the TCR and its Associated Signaling Proteins

Published on: March 22, 2012

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不同的蛋白质-蛋白质相互作用是TCR和含有4-1BB域的CAR介导的信号的基础

Samuel A Ritmeester-Loy1, Isabella H Draper1, Eric C Bueter1

  • 1Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA 98101, USA.

Science signaling
|March 5, 2024
PubMed
概括

化学抗原受体 (CAR) T细胞利用蛋白相互作用进行信号传递. 这项研究揭示了与T细胞受体 (TCR) 相比,CAR T细胞激活的独特信号通路,为改善CAR T细胞制造提供了洞察力.

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Measuring TCR-pMHC Binding In Situ using a FRET-based Microscopy Assay19:05

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