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Updated: Jul 1, 2025

Detecting Somatic Genetic Alterations in Tumor Specimens by Exon Capture and Massively Parallel Sequencing
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生殖线结构变异在全球范围内影响癌症转录组,包括与疾病相关的基因

Fengju Chen1, Yiqun Zhang1, Fritz J Sedlazeck2

  • 1Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA.

Cell reports. Medicine
|March 5, 2024
PubMed
概括

生殖系结构变异 (SVs) 在瘤中显著影响基因表达,影响数百个基因. 这些变异可以影响癌症的发展和患者的存活率,为基因测试和癌症治疗提供潜在的目标.

关键词:
在GWAS中,GWAS就是GWAS.在PCAWG中使用PCAWG.整体基因组的全癌症分析整个基因组的测序.癌症 癌症 癌症 癌症 癌症我们的eQTL是eQTL.表达方式 定量特征 loci loci细菌线的生殖线结构变体 结构变体结构变化的结构变化.

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