异常下调的FENDRR由阿雷科林提高ROS和肌纤维细胞激活通过缓解miR-214/MFN2轴

Yi-Wen Liao1, Cheng-Chia Yu2, Chang-Wei Hsieh3

  • 1Department of Medical Research, Chung Shan Medical University Hospital, Taichung 402, Taiwan; Institute of Oral Sciences, Chung Shan Medical University, Taichung 402, Taiwan.

概括

长非编码RNAFENDRR在口腔下纤维化 (OSF) 中至关重要,通过调节miR-214和线粒素2抑制肌纤维细胞激活. 它的下调与阿雷科林暴露有关,促进OSF的进展.

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