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Updated: Jul 1, 2025

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[在Caco-2肠道细胞屏障损伤模型上,银-寡糖和聚二的保护作用]

Na Li1, Wanqing Guo1, Rong Xiang1

  • 1West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.

Wei sheng yan jiu = Journal of hygiene research
|March 5, 2024
PubMed
概括

银糖寡糖 (GOS) 和聚德 (PDX) 益生菌显著增强肠道细胞屏障的完整性. 这种组合有效地减少了肠道的透性和炎症,提供了保护性益处.

关键词:
在Caco-2细胞中.银河体-橄糖酸盐.肠道细胞屏障 肠道细胞屏障聚德二糖是一种多德二.紧密结合蛋白质是一种紧密结合蛋白质.

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In the intricate landscape of the gastric lumen, excessive acid secretion disrupts the natural defense mechanisms, weakening the mucus-bicarbonate barrier. This vulnerability allows pepsin to infiltrate epithelial cells, digesting mucosal proteins and triggering erosion, leading to ulcer formation.
In this scenario, mucosal protective agents like sucralfate play an essential role. Sucralfate, a complex of sulfated sucrose and aluminum hydroxide, demonstrates its usefulness in acidic conditions,...
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