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Updated: Jul 1, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
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在乳腺癌中,BCAR4表达作为内分泌治疗耐药性的预测生物标志物

Muheng Liao1, Jace Webster2, Emily M Coonrod2

  • 1Division of Biostatistics, Washington University School of Medicine, St Louis, MO.

Clinical breast cancer
|March 5, 2024
PubMed
概括

高BCAR4基因表达与乳腺癌的内分泌疗法抵抗有关,影响患者的治疗结果,特别是在光线亚型中. 识别BCAR4有助于避免不有效的治疗.

关键词:
药物耐药性 药物耐药性 药物耐药性基因组学就是基因组学.

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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