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Updated: Jul 1, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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Published on: February 20, 2018

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神经元中一些本源GPCRs的特定药理和Gi/o蛋白反应

Chanjuan Xu1,2, Yiwei Zhou1,3, Yuxuan Liu1

  • 1Cellular Signaling Laboratory, Key Laboratory of Molecular Biophysics of Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Nature communications
|March 5, 2024
PubMed
概括

在使用敏感生物传感器的初级神经元中研究G蛋白结合受体 (GPCR) 揭示了与异质细胞相比不同的信号特性,突出了本地环境研究的需要.

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