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Updated: Jul 1, 2025

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
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Riboformer:一种深度学习框架,用于预测上下文依赖的翻译动态

Bin Shao1,2, Jiawei Yan3, Jing Zhang4

  • 1Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA. shaobinlx@gmail.com.

Nature communications
|March 5, 2024
PubMed
概括

深度学习工具Riboformer标准化了核糖体分析数据,以揭示基因序列如何影响蛋白质生产. 它有助于识别与疾病相关的翻译问题和导致核糖体停滞的序列动机.

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