全球对 prokaryotic 基因组的调查揭示了推动横向基因转移的生态进化压力
Marija Dmitrijeva1,2, Janko Tackmann1, João Frederico Matias Rodrigues1
1Department of Molecular Life Sciences and Swiss Institute of Bioinformatics, University of Zürich, Zurich, Switzerland.
Nature ecology & evolution
|March 5, 2024
概括
水平基因转移 (HGT) 驱动着 prokaryotic 进化. 这项研究表明,共同存在的物种交换更多的基因,专家主要与其他专家互动,塑造生态进化趋势.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 基因组学就是基因组学.
背景情况:
- 横向基因转移 (HGT) 对 prokaryotic 基因组进化至关重要.
- 由于环境数据有限,影响HGT的生态因素未得到充分研究.
- 以前的研究强调了进化对基因持久性的影响.
研究的目的:
- 研究 prokaryotes 中 HGT 的生态贡献.
- 分析HGT事件在不同环境中的分布和功能概况.
- 了解物种相互作用和息地偏好如何影响基因交换.
主要方法:
- 对个体基因树与物种树进行比较分析,以检测HGT事件.
- 在超过一百万个环境测序样本中评估基因交换 prokaryotes.
- 在HGT事件和物种共发生,相互作用,丰富性和息地专业化之间进行相关性分析.
主要成果:
- 对最近和古代的HGT事件观察到不同的功能概况.
- 进化早期转移的基因在当代物种中更为无处不在.
- 同时发生,相互作用和高丰度物种表现出更高的基因交换率.
- 与宿主相关的专家优先与其他专家交换基因;通用学家在息地之间显示一致的交换率.
结论:
- 生态因素,特别是物种相互作用和息地专业化,显著影响HGT动态.
- 在各种环境中,HGT在 prokaryotic 适应和多样化中发挥着关键作用.
- 这项研究提供了对 prokaryotic HGT.的生态进化趋势的大规模见解.
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