tRigon:一个R包和Shiny App用于整合性 (路径) 经济数据分析
David L Hölscher1,2, Michael Goedertier1,3, Barbara M Klinkhammer1
1Institute of Pathology, RWTH Aachen University Clinic, Aachen, Germany.
BMC bioinformatics
|March 5, 2024
概括
tRigon是整合性奥米克数据分析的新工具箱,简化了复杂的病理学数据解释. 该应用程序使研究人员能够在没有编码专业知识的情况下进行快速,可重复和全面的分析.
科学领域:
- 计算病理学计算病理学
- 生物信息学是一种生物信息学.
- 数据科学是数据科学.
背景情况:
- 病理学提供自动化组织病理学分析,但面临着高维数据,可变性和缺失的挑战.
- 对病理学数据进行快速和可理解的分析对于广泛实施至关重要.
- 现有的工具可能无法充分解决病理学数据分析的复杂性.
研究的目的:
- 开发一个用户友好的应用程序,用于快速,全面和可重复的病理学数据分析.
- 为了促进没有编码专业知识的研究人员进行探索性特征分析.
- 支持病理学和其他病理学数据集的整合和解释.
主要方法:
- 开发了tRigon (整合数据分析的工具箱),一个闪亮的应用程序.
- tRigon作为CRAN的R包提供,其源代码在GitLab上.
- 该应用程序可以在本地安装或通过网页界面在线访问.
主要成果:
- tRigon 在不同的硬件上展示了各种大小的数据集的快速计算.
- 该应用程序提供了一个用户友好的界面,用于探索性数据分析.
- 在低性能和高性能硬件上成功执行表明了广泛的适用性.
结论:
- tRigon使没有编码技能的研究人员能够进行自己的探索性分析.
- 该工具箱支持各种硬件上的病态和非病态数据集.
- tRigon促进了先进病理学分析的更广泛的实施和可访问性.
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