美国成年人体力活动和处方阿片类药物使用的分析:一个横截面研究
Junpeng Wu1, Panpan Yang1, Xiaodan Wu1
1Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The Key Laboratory of Precision Anesthesia & Perioperative Organ Protection, Guangzhou North Road, Guangzhou, 510515, Guangdong, China.
BMC public health
|March 5, 2024
概括
参与足够的体力活动 (PA),包括与交通相关的PA (TPA) 和休时间的PA (LTPA),与减少处方阿片类药物的使用有关. 然而,影响因阿片类药物的持续时间和强度而异,提供了潜在的政策指导.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 行为科学 行为科学
背景情况:
- 全球阿片类药物危机需要了解缓解处方阿片类药物使用的因素.
- 不同体力活动 (PA) 领域在减少处方阿片类药物使用中的具体作用仍在调查中.
研究的目的:
- 调查身体活动 (PA) 的各种领域与处方阿片类药物使用之间的关联.
- 检查不同PA领域与处方阿片类药物使用持续时间之间的关系.
主要方法:
- 从国家健康和营养检查调查 (NHANES) (2007-2020) 中对27943名美国成年人的横截面分析.
- 使用多变量后勤回归来评估职业相关的PA (OPA),交通相关的PA (TPA) 和休时间的PA (LTPA) 与处方阿片类药物的使用及其持续时间之间的关联.
- 通过分层和灵敏度分析来提高稳健性,并纳入适当的采样重量.
主要成果:
- 足够的总PA (≥150分钟/周),TPA和LTPA在多变量调整后与处方阿片类药物使用相反相关.
- 观察到一种剂量反应关系,增加PA持续时间与处方阿片类药物使用的几率较低相关.
- 足够的PA证明了对短期和长期阿片类药物使用的不同影响,对减少长期使用 (≥90天) 有好处,这取决于阿片类药物的强度.
结论:
- 充分参与总PA,TPA和LTPA与处方阿片类药物使用相反相关.
- 抗阿片和处方阿片类药物使用之间的关系是微妙的,取决于阿片类药物使用的持续时间和强度.
- 结果表明,PA干预可以为旨在解决阿片类药物危机的公共卫生政策提供信息.
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