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Updated: Jul 1, 2025

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
11:20

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

Published on: March 29, 2018

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独特的奇诺林方位塑造了修改后的阿帕特马到斯克莱洛斯的形状,以增强结合亲和力和骨类 anabolic 潜力

Amu Gubu1,2, Yuan Ma1,2,3, Sifan Yu1,4,5

  • 1Guangdong-Hong Kong-Macao Greater Bay Area International Research Platform for Aptamer-based Translational Medicine and Drug Discovery, Hong Kong SAR 999077, China.

Molecular therapy. Nucleic acids
|March 6, 2024
PubMed
概括

研究人员改进了一种aptamer来治疗骨质变异不完美 (OI). 修改后的阿帕特默通过向硬质素来增强骨的形成,为OI提供了潜在的治疗方法,没有心血管风险.

关键词:
MT:寡核酸:治疗方法和应用.结合性亲和力是一种结合性亲和力.骨类类合成药的潜在潜力.修改后的阿普塔默图书馆奇诺林修改 奇诺林修改斯克莱洛斯氨酸胺体

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