Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antiasthma Drugs: Methylxanthines01:24

Antiasthma Drugs: Methylxanthines

228
Theophylline, a member of the methylxanthine class of bronchodilators, has long been used in asthma management. While its exact mechanism of action is not fully understood, it is believed to have multiple effects on various cellular processes.
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
228
Adrenergic Agonists: Mixed-Action Agents01:28

Adrenergic Agonists: Mixed-Action Agents

709
Mixed-action adrenergic agonists, like ephedrine and pseudoephedrine, directly and indirectly affect adrenergic receptors. These agents stimulate adrenoceptors and indirectly release stored neurotransmitters, amplifying the adrenergic response.
Ephedrine and pseudoephedrine lack a catecholamine group, making them less susceptible to degradation by metabolic enzymes. They have increased oral bioavailability and lipophilicity, resulting in a longer duration of action. Their response is reduced by...
709
Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

2.8K
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
2.8K
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

2.7K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
2.7K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

294
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
294
Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

2.8K
Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
2.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Occupational hazard awareness and safety-related knowledge among EMS students: evidence of a potential gap.

Scientific reports·2026
Same author

Corrigendum to "LLM predicts human behavior: A BERT-based approach for conscientiousness personality trait detection from online content" [Acta Psychologica 266 (2026), 106832].

Acta psychologica·2026
Same author

Evaluation of Video-Based Instruction and a 360° Virtual Reality Module on Personal Protective Equipment Competency and Infection Prevention in Healthcare Settings: A Quasi-Experimental Study.

Healthcare (Basel, Switzerland)·2026
Same author

Immune and non-immune hydrops fetalis in a Saudi tertiary center: etiologies, antenatal predictors, perinatal outcomes, and one-year survival in a seven-year cohort.

Frontiers in pediatrics·2026
Same author

LLM predicts human behavior: A BERT-based approach for conscientiousness personality trait detection from online content.

Acta psychologica·2026
Same author

Low muscle mass in interstitial lung disease: a systematic review and meta-analysis of prevalence and clinical associations.

BMC pulmonary medicine·2026

相关实验视频

Updated: Jul 1, 2025

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
08:58

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

Published on: July 10, 2018

43.0K

甲基酸会导致慢性异性肺炎.

Dhafer Alghamdi1, Hamdan Jahdali1, Abdullah Alharbi1

  • 1Department of Pulmonology, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Annals of thoracic medicine
|March 6, 2024
PubMed
概括

甲基胺,一种治疗注意力缺陷多动症的药物,可能会导致eosinophilic肺炎. 这种罕见的疾病涉及肺炎,在停止服用药物后得到改善.

关键词:
过敏 过敏是一种过敏.慢性埃索诺菲尔性肺炎是一种慢性肺炎.药物诱导的肺损伤是药物引起的.甲基化甲基化

更多相关视频

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
08:44

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

6.1K
Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

22.8K

相关实验视频

Last Updated: Jul 1, 2025

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
08:58

Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography

Published on: July 10, 2018

43.0K
Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation
08:44

Identification and Characterization of Immunogenic RNA Species in HDM Allergens that Modulate Eosinophilic Lung Inflammation

Published on: May 30, 2020

6.1K
Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice
15:43

Long Term Chronic Pseudomonas aeruginosa Airway Infection in Mice

Published on: March 17, 2014

22.8K

科学领域:

  • 肺部病理学 肺部病理学
  • 药理学 药理学是指药理学的学科.
  • 毒理学 毒理学 毒理学

背景情况:

  • 注意缺陷多动症 (ADHD) 通常用兴奋剂药物治疗.
  • 甲基酸盐是一种广泛处方的中枢神经系统兴奋剂,用于ADHD.
  • 药物诱导的肺损伤是各种药物的公认但不常见的副作用.

研究的目的:

  • 报告一种可能由甲基酸诱导的eosinophilic肺炎病例.
  • 强调在呼吸道症状中考虑药物副作用的重要性.
  • 强调在疑似药物诱导的肺损伤时,支气管洗和活检的诊断实用性.

主要方法:

  • 一个38岁的男性患者的病例报告,他患有多动症和多动症在甲基酸盐.
  • 临床评估包括胸部成像 (地面玻璃不透明) 和支气管镜检查.
  • 支气管支气管洗液 (乙素细胞数) 和横支气管活检的分析.
  • 通过药物戒断和重新挑战来评估药物因果关系.

主要成果:

  • 患者呈现出渐进的呼吸短促和咳.
  • 胸部成像显示了双边地面玻璃不透明.
  • 支气管支气管洗显示了15%的乙氨基酸计数,活检证实了乙氨基酸性肺炎.
  • 症状随着类固醇治疗和甲基化物停止而消失,并在甲基化物再次挑战时复发,伴随着皮疹.

结论:

  • 甲基酸盐被强烈认为是这种患者患有eosinophilic肺炎的致病剂.
  • 这一案例强调了兴奋剂药物诱导罕见肺部不良事件的潜力.
  • 临床医生应保持高的药物诱导肺部疾病的怀疑指数,在患者呈现出无法解释的呼吸道症状,而在甲基胺.