在南非药房销售的天然降胆固醇补充剂的范围审查
Hyeon Bok Lee1, Razeeya Khan1, Muhammed Vally1
1Department of Pharmacy and Pharmacology, Division of Clinical Pharmacy, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Health SA = SA Gesondheid
|March 6, 2024
概括
自然降胆固醇补充剂 (NCLSs) 很受欢迎,但证据各不相同. 同酶Q10,益生菌和固醇显示出有前途,而其他NCLS成分需要更多的研究才能有效指导患者.
科学领域:
- 药理学和药理学和药理学.
- 基于证据的医学 基于证据的医学
- 营养保健品 营养保健品
背景情况:
- 脱脂血症涉及异常的胆固醇水平 (总,LDL,HDL).
- 患者经常使用天然降胆固醇补充剂 (NCLS).
- 关于NCLS的有效性和安全性,现有的信息有限.
研究的目的:
- 为了确定南非药房中可用的NCLS.
- 审查支持这些NCLS中的成分的科学证据.
主要方法:
- 使用乔安娜·布里格斯研究所 (JBI) 方法进行了范围审查.
- 鉴定和分析了17种NCLS产品.
- 文献审查集中在单个NCLS成分的证据上.
主要成果:
- 同酶Q10,益生菌和固醇显示出足够的支持科学证据.
- 对于许多其他NCLS成分,发现了有限的科学证据.
- 在不同NCLS组件的证据基础上存在显著的变化.
结论:
- 药剂师需要基于证据的NCLS指导,以提供知情的患者咨询.
- 进一步的研究是必要的,以验证各种NCLS成分的疗效.
- 本综述提供了关于NCLSs的基于证据的决策的基本文件.
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