在患有低体积前列腺癌的男性中进行最佳的全身治疗
Akshat Saxena1, Jack Andrews2, Alan Haruo Bryce3
1Department of Oncology.
Current opinion in urology
|March 6, 2024
概括
确定低体积前列腺癌的定义至关重要. 像PSMA PET扫描这样的先进成像和考虑转移时间是改进转移性激素敏感前列腺癌治疗策略的关键.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 低体积前列腺癌是转移性激素敏感前列腺癌的预后类别.
- 低体积疾病的定义经常在各种前列腺癌状态中不一致地应用.
- 本综述考察了低体积前列腺癌不断变化的定义,生物学和治疗证据.
结论:
- 低体积前列腺癌的管理 (CHAARTED标准) 可能依赖于转移时间,因为没有经过验证的生物标志物.
- 建议包括新型荷尔蒙疗法 (NHT) 双重剂与或没有MDT用于甲时性疾病,以及NHT双重剂与或没有MDT和前列腺导向辐射用于同步性疾病.
- 未来的策略可能涉及MDT,而不是通过基因组学和PSMA PET成像识别的寡基因转移性疾病的系统治疗.
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