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Updated: Jul 1, 2025

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骨髓氧化酶抑制剂mitiperstat (AZD4831) 在预期的治疗剂量下不会延长QT间隔

Joanna Parkinson1, Jesper Sundell2, Dinko Rekić3

  • 1Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

Pharmacology research & perspectives
|March 6, 2024
PubMed
概括

米蒂珀斯塔特是一种髓氧化酶抑制剂,不会在健康志愿者中延长QT间隔. 度-QT建模证实在治疗度下没有显著风险,支持其对心力衰竭和其他疾病的安全性.

关键词:
延长了QT的时间生物制药 生物制药 生物制药药物安全 药物安全心脏衰竭是因为心脏衰竭.建模和模拟的模型和模拟.

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