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老年人的肺癌结局:查中的潜在差异

Anupama Singh¹, Emanuele Mazzola², Yue Xie²

¹Division of Thoracic Surgery, Brigham and Women's Hospital, Boston, MA, USA.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

|March 6, 2024

概括

患有非小细胞肺癌 (NSCLC) 的80岁以上老年患者的诊断不太准确,并接受的手术较少,导致与年轻患者相比生存结果更差.

科学领域:

在瘤学瘤学.
老年医学老年医学
公共卫生公共卫生

背景情况:

肺癌是导致死亡的主要原因,特别是在老年人中.
对患有非小细胞肺癌 (NSCLC) 的老年患者的最佳治疗策略仍然是积极研究的领域.

研究的目的:

分析和比较70-79岁和80-90岁的老年患者肺癌的临床结果.
根据年龄组确定诊断,治疗和生存的差异.

主要方法:

从国家癌症数据库 (2004-2017) 追溯分析了466,051名患有NSCLC的患者.
患者被分为两组:70-79岁 (A组) 和80-90岁 (B组).
卡普兰-梅尔曲线被用来估计按年龄组和癌症阶段的整体存活率.

主要成果:

与70-79岁 (A组) 患者相比,80-90岁 (B组) 的患者更频繁地使用不那么侵入性,不那么准确的方法进行诊断.
B组患者在临床阶段IA被诊断的可能性较小,并且接受手术干预的可能性明显较小.
与A组相比,生存分析显示B组在所有临床和病理阶段的预后较差.

结论:

患有NSCLC的老年患者 (80-90岁) 面临诊断和治疗方面的挑战,包括诊断措施不太准确和手术干预率降低.
这些差异导致最年长年龄组的生存结果较差.
需要进一步的研究来优化老年人群中NSCLC的管理.

关键词:

不平等的差异差异的差异肺癌查肺癌查肺癌查八分生殖者八分生殖者

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