相关实验视频
Updated: May 5, 2026
06:40
Simple and Computer-assisted Olfactory Testing for Mice
Published on: June 15, 2015
10.1K
嗅觉训练对COVID-19诱导的嗅觉丧失的影响
E J A Schepens1, C J M de Haas2, E M Postma3
1Department of Otorhinolaryngology- Head and Neck Surgery, University Medical Center Utrecht, Utrecht, the Netherlands; Brain Center, University Medical Center Utrecht, Utrecht, the Netherlands.
Rhinology
|March 6, 2024
概括
嗅觉训练在COVID-19引起的嗅觉丧失患者中显著改善了嗅觉功能. 然而,遵守训练方案与嗅觉改善没有相关性.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 传染性疾病 传染性疾病
背景情况:
- 后病毒性嗅觉功能障碍是COVID-19的一个常见症状.
- 嗅觉训练对COVID-19相关的嗅觉丧失的有效性尚未得到充分证实.
研究的目的:
- 为了研究COVID-19导致嗅觉丧失的患者嗅觉训练的有效性.
主要方法:
- 一项病例对照研究比较了一组执行12周嗅觉训练 (n=111) 的队列与对照组 (n=50).
- 嗅觉功能使用嗅探棒测试 (SST) 进行评估,在基线和12周后测量值,歧视和识别 (TDI) 评分.
- 每天监测治疗坚持,并分析其与TDI得分的关联.
主要成果:
- 在嗅觉训练组和对照组之间观察到心理物理嗅觉功能的显著差异.
- 两组之间的TDI得分差异中位数为2.00.
- 坚持嗅觉训练和嗅觉功能的改善之间没有发现显著的关联.
结论:
- 嗅觉训练在COVID-19诱导的嗅觉障碍患者中对心理物理嗅觉功能的显著中等益处.
- 虽然嗅觉训练似乎有利,但粘附水平与嗅觉功能的恢复程度没有相关性.
相关概念视频
01:25Olfaction
40.5K
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
40.5K
01:03Olfactory Receptors: Location and Structure
10.6K
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
10.6K
01:20Physiology of Smell and Olfactory Pathway
13.2K
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...
13.2K