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Updated: Jul 30, 2026

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在乳腺癌中对TUSC2表达的免疫组织化学和分子评估

Leyla Tekin1, Tuba Edgünlü2, Deniz Genç3

  • 1Faculty of Medicine, Pathology Department, Muğla Sıtkı Koçman University, Muğla, Turkey. dr.ltekin@hotmail.com.

Molecular biology reports
|March 6, 2024
PubMed
概括

在乳腺癌组织中,瘤抑制候选物2 (TUSC2) 的表达显著减少或消失. 较低的TUSC2水平与瘤大小和扩散的增加相关,这表明它在乳腺癌发展中的作用.

关键词:
乳腺癌 乳腺癌 乳腺癌这是瘤等级的瘤.瘤的大小 瘤的大小瘤抑制剂候选人2表达方式

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...