患有无形皮肤炎的儿童认知障碍的症状
Emily Z Ma1,2, Hannah R Chang3,2, Sarah Radtke4
1University of Maryland School of Medicine, Baltimore.
JAMA dermatology
|March 6, 2024
概括
儿科亚型皮肤炎 (AD) 与儿童的学习和记忆问题有关,特别是那些患有ADHD等神经发育障碍的儿童. 这凸显了对患有阿兹海默症的风险儿童进行认知评估的需要.
科学领域:
- 儿科皮肤病学 儿童皮肤病学
- 神经科学是一个神经科学.
- 公共卫生 公共卫生
背景情况:
- 亚托皮炎 (AD) 越来越多地被认为是一种可能影响儿童认知功能的疾病.
- 以前的研究经常使用诊断作为认知障碍的代理,使基于症状的关联不清楚.
- 了解儿科阿尔茨海默病中特定的风险亚群对于有针对性的干预至关重要.
研究的目的:
- 调查美国儿童中亚型皮肤炎 (AD) 和认知障碍 (学习和记忆障碍) 症状之间的关联.
- 为了确定这种关联在患有或没有神经发育并发症的儿童中是否有所不同,例如ADHD,发育迟缓或学习障碍.
主要方法:
- 采用2021年美国国家卫生访谈调查数据进行的横截面研究.
- 包括17岁或以下没有智力障碍或自闭症的儿童.
- 亚托皮炎 (AD) 和认知症状 (学习/记忆障碍) 是家长/护理人员报告的.
主要成果:
- 与没有阿兹海默症的儿童相比,患有阿兹海默症的儿童学习 (10.8%) 和记忆 (11.1%) 困难的几率显著更高.
- 阿尔茨海默病与学习和记忆困难的可能性增加有关,即使在调整了社会人口统计学因素和其他过敏状况之后.
- 在患有神经发育并发症 (包括ADHD和学习障碍) 的儿童中,AD和记忆障碍之间的关联显著更强 (几率增加2至3倍).
结论:
- 儿科亚型皮肤炎 (AD) 与学习和记忆困难的几率增加有关.
- 这种关联主要是由同时出现神经发育疾病的儿童驱动的.
- 优先考虑AD和神经发育障碍儿童的认知评估可能会改善风险分层和风险管理.
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