通过喘控制测试评估夜间呼吸道症状是否受到伴随性疾病的影响?
Alida Benfante1, Alessandra Tomasello1, Chiara Caponetto1
1Division of Respiratory Medicine, "Paolo Giaccone" University Hospital, University of Palermo, Palermo, Italy.
夜间喘症状可能会因未被诊断的睡眠障碍而恶化,而不仅仅是喘本身. 需要进一步评估,以确定喘患者夜间觉醒的根本原因.
科学领域:
- 肺部病理学 肺部病理学
- 睡眠医学 睡眠医学
背景情况:
- 夜间症状在喘中很普遍,通常与过度的夜间气道狭窄有关.
- 伴随性疾病与喘本身对夜间唤醒的贡献仍然不清楚.
研究的目的:
- 研究喘控制与诸如鼻炎,胃食道逆流症 (GERD) 和阻塞性睡眠呼吸暂停综合征 (OSAS) 等并发症之间的关系.
- 通过使用喘控制测试 (ACT) 确定可归因于这些并发症的喘控制不良的比例.
主要方法:
- 100名喘患者填写了问卷,包括ACT,总5症状评分,GERD影响量表,匹兹堡睡眠质量指数 (PSQI) 和睡眠障碍问卷 (SA-SDQ).
- 根据ACT得分,患者被分为完全控制 (FC),部分控制 (PC) 和不受控制 (UC) 的类别.
主要成果:
- GERD和鼻炎与ACT分数没有显著关联.
- 在喘控制不良 (ACT分数较低) 和PSQI分数较高 (p=0.002) 之间观察到显著的正相关性.
- 同样,SA-SDQ得分随着喘控制的减少而显著增加 (p=0.005),表明睡眠障碍和喘控制之间存在联系.
结论:
- 喘控制不良与潜在的睡眠障碍有显著的关联,这是PSQI和SA-SDQ得分所表明的.
- 这些发现表明,睡眠问题,而不仅仅是喘或其他并发症,如GERD和鼻炎,可能会显著影响喘控制.
- 对睡眠障碍进行全面评估对于有效管理夜间喘症状至关重要.
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