在亚洲患者中查实践和HYDROXYCHLOROQUINE视网膜病的晚期诊断
1Department of Ophthalmology, Hanyang University Hospital, Hanyang University College of Medicine, Seoul, Korea.
Retina (Philadelphia, Pa.)
|March 6, 2024
概括
对氧化甲视网膜病变查指南的不充分遵守,特别是延迟的初始监测,与亚洲患者的晚期诊断有关. 这强调了需要及时查以预防视力丧失的必要性.
科学领域:
- 眼科医生 眼科 眼科
- 药物监督 药物监督 药物监督
- 视网膜疾病 视网膜疾病
背景情况:
- 氧化 (HCQ) 视网膜病变是HCQ治疗的一个严重不良影响.
- 早期发现HCQ视网膜病变对于预防不可逆转的视力丧失至关重要.
- 存在查指南来监测HCQ视网膜病变,但坚持和有效性各不相同.
研究的目的:
- 调查查实践与亚洲患有氧化网膜病变的亚洲患者诊断时间之间的关联.
- 确定导致HCQ视网膜病变晚诊断的因素.
主要方法:
- 一项回顾性研究包括92名被诊断患有HCQ视网膜病变的韩国患者.
- 根据视网膜病变的阶段,患者被分为晚期和早期诊断组.
- 查实践 (时间,方式) 和遵守美国眼科医学会指导方针在各组之间进行了比较.
主要成果:
- 只有5.3%的晚期诊断患者有适当的基线和初始监测时间.
- 在5年初始监测和晚期和早期诊断组之间的年度监测中观察到显著差异 (P=0.003,P<0.001).
- 延迟第一次监测检查 (P<0.001),年龄较小 (P=0.028),以及第一次监测的时间与晚诊断有关.
结论:
- 对眼科指导方针的不良遵守,特别是延迟的初始监测,与晚期诊断HCQ视网膜病变有关.
- 及时和适当的查对于早期发现和管理HCQ视网膜病变至关重要.
- 这些发现强调了患者和医生对HCQ视网膜病变查方案的教育的重要性.
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