使用基于的电子烟和尼古丁袋来减少低社会经济地位的成年人吸烟的伤害:试点随机对照试验
Jaqueline C Avila1, Dale Dagar Maglalang2,3, Nicole L Nollen4
1Department of Gerontology, University of Massachusetts Boston, Boston, MA, USA.
低社会经济地位 (SES) 的吸烟者通过切换到电子烟 (EC) 或尼古丁袋 (ONP) 显著减少了日常吸烟. 这些替代性尼古丁传递系统 (ANDS) 显示出对这一群体的减害工具的希望.
科学领域:
- 减少烟草的危害 减少烟草的危害
- 公共卫生干预措施 公共卫生干预措施
- 尼古丁成研究 尼古丁成研究
背景情况:
- 替代尼古丁输送系统 (ANDS),包括电子烟 (EC) 和口服尼古丁袋 (ONP),为不愿戒烟的人提供潜在的戒烟替代方案.
- 这项试点研究专门研究了EC和ONP在低社会经济地位 (SES) 的吸烟者群体中降低危害的有效性.
研究的目的:
- 评估EC和ONP在没有打算戒烟的低SES成年吸烟者的降害潜力.
- 在使用EC,ONP或没有干预 (控制) 8周后,评估香烟消费 (每天香烟 - CPD) 的变化.
主要方法:
- 一项随机对照试验涉及45名成年每日吸烟者,家庭收入低于联邦贫困线的250%,并没有打算在30天内戒烟.
- 参与者被随机分配 (2:2:1) 到8周的5%尼古丁EC,4毫克ONP或仅评估的对照组.
- 测量的主要结果是从基线到第8周的CPD在组内变化.
主要成果:
- 共有33名参与者完成了为期8周的研究.
- 使用EC的参与者显示,CPD的平均值从14.7降至2.9 (p < .001).
- 使用ONP的参与者显示,CPD的平均值从15.0降至8.3 (p = .01).
- 在EC组的28.6%和ONP组的8.3%中,完全从吸烟转换为指定的ANDS产品.
结论:
- 切换到EC或ONP导致低SES吸烟者减少了香烟的消费.
- 这些发现表明,ANDS可以作为有效的减少危害的工具,有可能减轻弱势群体中与烟草有关的健康差异.
- 这项研究提供了支持使用EC和ONP的新证据,用于那些不愿意戒掉传统香烟的吸烟者.
更多相关视频
10:44Comparing the Effects of Electronic Cigarette Vapor and Cigarette Smoke in a Novel In Vivo Exposure System
Published on: May 24, 2017
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
相关概念视频
Stimulants
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Drugs Acting on Autonomic Ganglia: Stimulants
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
Inhaled Medications
CNS Depressants: Alcohol and Nicotine
Stress Prevention and Stress Management Techniques IV
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
